Osteoarthritis
July 2, 2019
Metformin reduces risk of knee OA progression in patients with obesity
Metformin use was linked to a reduced rate of medial cartilage loss that may, in turn, reduce the risk for total knee replacement among patients with osteoarthritis who are obese, according to data published in Arthritis Research & Therapy. “Current treatments for osteoarthritis are modestly effective in pain relief with short-term effects, with no treatments that slow disease…
July 1, 2019
Simple clinical test provides a quick clue to knee OA progression
Clinical examination using the patellofemoral grind test can help predict which patients with knee pain are most likely to progress to osteoarthritis requiring arthroplasty. A large study of more than 4,000 participants from the National Institutes of Health Osteoarthritis Initiative found about 16% had a positive patellofemoral grind test – assessed as pain on distal force at…
June 2, 2018
Statin Initiation Not Associated With Incident Hand Osteoarthritis
The initiation of statin therapy is not associated with an increased risk for the development of hand osteoarthritis (OA), regardless of age, gender, statin agent, statin dose, preexisting dyslipidemia, or duration of treatment, according to the results of a propensity score-matched sequential cohort study using data from the UK-based Clinical Practice Research Datalink. Findings from the analysis…
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