Posts Tagged: Obesity
July 2, 2019
Metformin reduces risk of knee OA progression in patients with obesity
Metformin use was linked to a reduced rate of medial cartilage loss that may, in turn, reduce the risk for total knee replacement among patients with osteoarthritis who are obese, according to data published in Arthritis Research & Therapy. “Current treatments for osteoarthritis are modestly effective in pain relief with short-term effects, with no treatments that slow disease…
July 1, 2019
Simple clinical test provides a quick clue to knee OA progression
Clinical examination using the patellofemoral grind test can help predict which patients with knee pain are most likely to progress to osteoarthritis requiring arthroplasty. A large study of more than 4,000 participants from the National Institutes of Health Osteoarthritis Initiative found about 16% had a positive patellofemoral grind test – assessed as pain on distal force at…
August 27, 2018
Obesity Associated With Increased Risk for Gout
Overall obesity measured by body mass index (BMI) is associated with an increased risk for gout and with higher serum urate concentrations, according to the results of a Mendelian randomization study published in Rheumatology. The investigators sought to explore whether overall obesity, as measured by BMI, and abdominal obesity, as measured by waist-to-hip ratio (WHR) adjusted for BMI,…
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